Buy Danocrine (Danazol) antigonadotropin and anti-allergic drug
Cheap qualitative Danazol 50 mg, 100 mg, 200 mg capsules online
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DANOCRINE (DANAZOL) CAPSULES: CLINICAL PHARMACOLOGY
Danocrine (Danazol) suppresses the pituitary-ovarian axis. This suppression is probably a combination of depressed hypothalamic-pituitary response to lowered estrogen production, the alteration of sex steroid metabolism, and interaction of danazol with sex hormone receptors. The only other demonstrable hormonal effect is weak androgenic activity. Danocrine depresses the output of both follicle-stimulating hormone (FSH) and luteinizing hormone (LH).
Recent evidence suggests a direct inhibitory effect at gonadal sites and a binding of Danocrine (Danazol) capsules to receptors of gonadal steroids at target organs. In addition, Danocrine has been shown to significantly decrease IgG, IgM and IgA levels, as well as phospholipid and IgG isotope autoantibodies in patients with endometriosis and associated elevations of autoantibodies, suggesting this could be another mechanism by which it facilitates regression of the disease.
In the treatment of endometriosis, Danazol (Danocrine) alters the normal and ectopic endometrial tissue so that it becomes inactive and atrophic. Complete resolution of endometrial lesions occurs in the majority of cases.
Changes in vaginal cytology and cervical mucus reflect the suppressive effect of Danocrine on the pituitary-ovarian axis.
In the treatment of fibrocystic breast disease, Danazol (Danocrine) capsules usually produce partial to complete disappearance of nodularity and complete relief of pain and tenderness. Changes in the menstrual pattern may occur.
Generally, the pituitary-suppressive action of Danocrine is reversible. Ovulation and cyclic bleeding usually return within 60 to 90 days when therapy with this medication is discontinued.
In the treatment of hereditary angioedema, Danocrine (Danazol) at effective doses prevents attacks of the disease characterized by episodic edema of the abdominal viscera, extremities, face, and airway which may be disabling and, if the airway is involved, fatal. In addition, Danocrine corrects partially or completely the primary biochemical abnormality of hereditary angioedema by increasing the levels of the deficient C1 esterase inhibitor (C1EI). As a result of this action the serum levels of the C4 component of the complement system are also increased.
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Danocrine prescribing information
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